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RaTG13 and the origin of SARS-CoV-2
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Characteristics of the SARS-CoV-2 virus relevant to the determination of its origin
RaTG13
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Bats, snakes or pangolins? Inside the hunt for the animal behind the coronavirus outbreak | WIRED UK
https://www.wired.co.uk/article/coronavirus-bats-snakes-pangolins
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
Btw, they say RaTG13 was sequenced in 2018 but Ping Yu's master's thesis (supervised by Zhengli Shi and submitted in June 2019) still calls it Ra4991. Anyway, like w/ the bat cages, that SARS-CoV-2's closest known relative came along under an unref'ed alias is def. not relevant.
https://twitter.com/AntGDuarte/status/1405112630428250116
Mojiang mines and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
By the way, did anyone actually make the RaTG13 virus and plate it in cells, or is it still just a sequence in a computer? Quote Tweet
https://twitter.com/angoffinet/status/1405543470756818944
RaTG13 and the origin of SARS-CoV-2
Coexistence of multiple coronaviruses in several bat colonies in an abandoned mineshaft
https://link.springer.com/content/pdf/10.1007/s12250-016-3713-9.pdf
RaTG13 and the origin of SARS-CoV-2
Shi Zhengli and the origin of SARS-CoV-2
Coronavirus Related to SARS-CoV-2 Found in Chinese Mine in 2013 Was Sent to Wuhan Lab
https://www.newsweek.com/coronavirus-related-sars-cov-2-found-chinese-mine-2013-was-sent-wuhan-lab-1515625
Chinese Academy of Sciences (CAS)
Coronaviruses (CoV)
Mojiang mines and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Wuhan Institute of Virology and the origin of SARS-CoV-2
Did Covid-19 Coronavirus Escape From A Lab In Wuhan China? Trump Supporters Are Spreading The Rumor, But There Is No Proof
https://www.buzzfeednews.com/article/ryanhatesthis/coronavirus-rumors-escape-lab-china-fox-news-trump
2017 China and the Trump administration
RaTG13 and the origin of SARS-CoV-2
Rush Limbaugh
SARS-CoV-2 conspiracy theories
The Epoch Times
The lab-leak theory of the origin of SARS-CoV-2
The media and the origin of SARS-CoV-2
Tom Cotton and the lab-leak theory of SARS-CoV-2
Wuhan Institute of Virology and the origin of SARS-CoV-2
Did the Coronavirus Escape From a Lab?
https://nymag.com/intelligencer/article/coronavirus-lab-escape-theory.html
1971 EcoHealth Alliance (EHA)
2020 Anthony Fauci and the Covid-19 pandemic
2021-01 Did the Coronavirus Escape From a Lab?
Biosafety Level 4 (BSL-4)
Intermediate horseshoe bat
Peter Daszak and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Ralph Baric and the origin of SARS-CoV-2
SARS-CoV
SARS-CoV-1
Shi Zhengli and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
Wuhan Institute of Virology (WIV)
Experts know the new coronavirus is not a bioweapon. They disagree on whether it could have leaked from a research lab - Bulletin of the Atomic Scientists
https://thebulletin.org/2020/03/experts-know-the-new-coronavirus-is-not-a-bioweapon-they-disagree-on-whether-it-could-have-leaked-from-a-research-lab/
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The zoonotic-spillover theory of the origin of SARS-CoV-2
I since learned that some labs are trying to construct the RaTG13 virus, but no results yet. My 5 cents: the virus will be unstable and cannot be obtained.
https://twitter.com/angoffinet/status/1405867539104555011
RaTG13 and the origin of SARS-CoV-2
I think we should not compare the differences between RaTG13 and Sarscov2, to chimps and humans. First of all the the virus is just 30,000 bases. And in this era of modern techniques, with a virus like 96.2 close, can be used for a synthetic construct. Or other ways can be used.
https://twitter.com/MonaRahalkar/status/1406289884562788355
RaTG13 and the origin of SARS-CoV-2
I would begin by making ratg13 and prove that it can grow in vero or bat cell lines. That would already be significant progress.
https://twitter.com/angoffinet/status/1406296246675988482
RaTG13 and the origin of SARS-CoV-2
Image of document
https://twitter.com/JollyKJo/status/1404854976996777987/photo/1
2015-11 A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
Dates of the earliest cases of Covid-19 infection
Mojiang mines and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
In hunt for Covid’s origin, new studies point away from lab leak theory | Coronavirus | The Guardian
https://www.theguardian.com/world/2021/jun/18/in-hunt-for-covids-origin-new-studies-point-away-from-lab-leak-theory
Anthony Fauci and the origin of SARS-CoV-2
David Relman and the origin of SARS-CoV-2
Jeremy Farrar and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
SARS-CoV-2 furin cleavage site and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The media and the origin of SARS-CoV-2
Molecular Biology Clues Portray SARS-CoV-2 as a Gain-of-Function Laboratory Manipulation of Bat CoV RaTG13
https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00274
2020 Anthony Fauci and the Covid-19 pandemic
Gain-of-function research and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
My thoughts about the Yan whistleblower report on SARS2 origins have been percolating over the past few very busy days. I'm ready to share them in this thread: (1) why+how whistleblowers must be protected (2) what the report gets right and what it gets wrong
https://twitter.com/Ayjchan/status/1306393772985638913
RaTG13 and the origin of SARS-CoV-2
The Chinese government and the origin of SARS-CoV-2
Yan Limeng and the origin of SARS-CoV-2
Opinion | Where Did the Coronavirus Come From? What We Already Know Is Troubling. - The New York Times
https://www.nytimes.com/2021/06/25/opinion/coronavirus-lab.html
1979-04 Sverdlovsk anthrax leak
2020-02 Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19
Biosafety Level 2 (BSL-2)
DRASTIC and the lab-leak theory of SARS-CoV-2
Dates of the earliest cases of Covid-19 infection
Laboratory accidents
Peter Daszak and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Ralph Baric and the origin of SARS-CoV-2
SARS-CoV-2 furin cleavage site and the origin of SARS-CoV-2
Shi Zhengli and the origin of SARS-CoV-2
The Chinese government and the origin of SARS-CoV-2
The question of whether the Wuhan Institute of Virology kept live bats before the Covid-19 outbreak
Origin of Covid — Following the Clues | by Nicholas Wade | May, 2021 | Medium
https://nicholaswade.medium.com/origin-of-covid-following-the-clues-6f03564c038
2020 Anthony Fauci and the Covid-19 pandemic
2021-05 Origin of Covid — Following the Clues
Biosafety Level 2 (BSL-2)
Biosafety Level 4 (BSL-4)
Covid-19 and ACE2
Peter Daszak and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Scientific methodology
Shi Zhengli and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The zoonotic-spillover theory of the origin of SARS-CoV-2
Wuhan Institute of Virology and the origin of SARS-CoV-2
RaTG13 & most probably RaTG15 are simply copypasted together / non-existing-in-nature genomes. The sequences look like virions, but... RaTG13 is a fabrication, real smoking guns: ZC45 & ZCX21, almost never mentioned, always derailed if discussions arise.
https://twitter.com/Bobby_Network/status/1406567683127234565
RaTG13 and the origin of SARS-CoV-2
SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects | Nature Structural & Molecular Biology
https://www.nature.com/articles/s41594-020-0468-7
RaTG13 and the origin of SARS-CoV-2
SARS-CoV-2 furin cleavage site and the origin of SARS-CoV-2
SARS-CoV-2's claimed natural origin is undermined by issues with genome sequences of its relative strains: Coronavirus sequences RaTG13, MP789 and RmYN02 raise multiple questions to be critically addressed by the scientific community - PubMed
https://pubmed.ncbi.nlm.nih.gov/34046923/
RaTG13 and the origin of SARS-CoV-2
SARS-CoV-2′s claimed natural origin is undermined by issues with genome sequences of its relative strains
https://onlinelibrary.wiley.com/doi/full/10.1002/bies.202100015
RaTG13 and the origin of SARS-CoV-2
The zoonotic-spillover theory of the origin of SARS-CoV-2
Something else weird about RaTG13. As some know, there are 2 versions of it in GenBank with 6 nt diffs. As @notoriousFIL noticed, those diffs have directionality: all ver2 nts are identical to those in SARS2. Why?
https://twitter.com/ydeigin/status/1403138004869423105
RaTG13 and the origin of SARS-CoV-2
Story of how 'amateur sleuths' forced world to consider Wuhan lab leak theory about Covid
https://theprint.in/world/story-of-how-amateur-sleuths-forced-world-to-consider-wuhan-lab-leak-theory-on-covid-origin/671862/
DRASTIC and the lab-leak theory of SARS-CoV-2
Peter Daszak and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Shi Zhengli and the origin of SARS-CoV-2
Tackling Rumors of a Suspicious Origin of nCoV2019 - nCoV-2019 Evolutionary History - Virological
https://virological.org/t/tackling-rumors-of-a-suspicious-origin-of-ncov2019/384
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The COVID-19 Lab Leak Theory Is Short on Evidence and Long on Guesswork
https://foreignpolicy.com/2021/06/15/lab-leak-theory-doesnt-hold-up-covid-china/
2021-01 Did the Coronavirus Escape From a Lab?
2021-05 Origin of Covid — Following the Clues
Eddie Holmes and the origin of SARS-CoV-2
Kristian Andersen and the origin of SARS-CoV-2
Laboratory accidents
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The Lab-Leak Theory: Inside the Fight to Uncover COVID-19’s Origins | Vanity Fair
https://www.vanityfair.com/news/2021/06/the-lab-leak-theory-inside-the-fight-to-uncover-covid-19s-origins
1971 EcoHealth Alliance (EHA)
2020-02 Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19
Biosafety Level 2 (BSL-2)
Biosafety Level 4 (BSL-4)
Chris Park and the US State Department
DRASTIC and the lab-leak theory of SARS-CoV-2
Gain-of-function research and the origin of SARS-CoV-2
Peter Daszak and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Ralph Baric and the origin of SARS-CoV-2
Shi Zhengli and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The genetic structure of SARS-CoV-2 does not rule out a laboratory origin
https://onlinelibrary.wiley.com/doi/full/10.1002/bies.202000240
DRASTIC and the lab-leak theory of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
The scientists who say the lab-leak hypothesis for SARS-CoV-2 shouldn't be ruled out | MIT Technology Review
https://www.technologyreview.com/2021/03/18/1021030/coronavirus-leak-wuhan-lab-scientists-conspiracy/
Biosafety Level 4 (BSL-4)
Charles Calisher
David Relman and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
Wuhan Institute of Virology (WIV)
Then why has nobody produced ratg13. That would be a superb tool providing arguments for a zoonosis. My guess they tried but failed because ratg13 is not a real virus sequence.
https://twitter.com/angoffinet/status/1406293140500267011
RaTG13 and the origin of SARS-CoV-2
Why the Covid-19 'Lab Leak Theory" Needs Another Look | Medium
https://donaldgmcneiljr1954.medium.com/how-i-learned-to-stop-worrying-and-love-the-lab-leak-theory-f4f88446b04d
2020 Anthony Fauci and the Covid-19 pandemic
2021-05 How I Learned to Stop Worrying And Love the Lab-Leak Theory
Peter Daszak and the origin of SARS-CoV-2
RaTG13 and the origin of SARS-CoV-2
Shi Zhengli and the origin of SARS-CoV-2
The lab-leak theory of the origin of SARS-CoV-2
You have some serious catching up to do
https://twitter.com/AntGDuarte/status/1405105006328664071
RaTG13 and the origin of SARS-CoV-2